Providing improved image quality during brain tumor resection

SonoClear is an acoustic coupling fluid that reduces image artefacts in ultrasound imaging.


SonoClear® image examples

Using Saline or Ringer as coupling fluid in large resection cavities may create artifacts that reduces the ultrasound image quality. The noise that occur, often at the bottom of resection cavities, is seen as unwanted brightness below the resection cavity in the images above. We are working closely with leading surgeons to solve this problem.

SonoClear reduces image artefacts by mimicking the physical properties of brain tissue.

SonoClear has been used in a Phase 1 clinical trial enrolling 15 patients. A significant improvement of image quality was observed with SonoClear.

– Geirmund Unsgård, Head of Neurosurgery Department at St. Olavs Hospital, Trondheim, Norway.

Image with visual parallax effect

Relevant publications:

Norwegian superfluid is now helping brain surgeons.

Ultrasound imaging in neurosurgery: approaches to minimize surgically induced image artefacts for improved resection control.

Animal study assessing safety of an acoustic coupling fluid that holds the potential to avoid surgically induced artifacts in 3D ultrasound guided operations

SINTEF’s prize for outstanding research


Financially supported by: